The endgame in Diablo 4 offers a challenging and rewarding experience to everyone. With the introduction of new bosses and items, including the formidable Uber Andariel, there are now more options for endgame farming.
The endgame boss loot table provides the details of the specific drops from defeating each boss including the latest Uniques introduced in Season 4. Understanding the loot tables of these bosses is essential to maximize your gameplay experience.
Lord Zir loot table
Go to the Fractured Peaks and reach the Darkened Way area. Once you enter the Ancient’s Seat dungeon, you must use Exquisite Blood to summon Lord Zir. The Exquisite Blood can be obtained from Legion events and defeating World Bosses.

Here’s Lord Zir’s loot table as seen on Backdash:
Character Classes | Uniques |
Necromancer | Bloodless Scream, Deathspeaker’s Pendant, Mutilator Plate, Ring of Mendein, Howl from Below |
Rogue | Condemnation, Windforce, Eaglehorn, Beastfall Boots, Word of Hakan |
Sorcerer | Staff of Lam Esen, The Oculus, Gloves of the Illuminator, Esu’s Heirloom, Starfall Coronet |
Barbarian | Battle Trance, Hellhammer, Fields of Crimson, 100,000 Steps, Ring of the Ravenous, Ancients’ Oath |
Druid | Waxing Gibbous, Insatiable Fury, Unsung Ascetic’s Wraps, Hunter’s Zenith, Storm’s Companion |
All classes | Razorplate, Yen’s Blessing, Penitent Greaves, Temerity |
The Beast in the Ice loot table
Head to the Desolate Islands in the Fractured Peaks and locate the Glacial Fissure dungeon. Enter the dungeon and ensure you have the Fissure Nightmare Sigil, crafted with Distilled Fear and Sigil Powder. The Beast in the Ice can be summoned now by using the Nightmare Sigil.

You are eligible for the following Uniques once you defeat Beast in the Ice:
Character Classes | Uniques |
Necromancer | Deathspeaker’s Pendant, Howl from Below, Bloodless Scream, Mutilator Plate, Ring of Mendeln |
Rogue | Eaglehorn, Condemnation, Beastfall Boots, Windforce, Word of Hakan |
Sorcerer | Starfall Coronet, Staff of Lam Esen, Gloves of the Illuminator, Esu’s Heirloom, The Oculus |
Barbarian | Hellhammer, Fields of Crimson, Battle Trance, Ring of the Ravenous, Ancients’ Oath, 100,000 Steps |
Druid | Waxing Gibbous, Insatiable Fury, Storm’s Companion, Unsung Ascetic’s Wraps, Hunter’s Zenith |
All classes | Frostburn, Paingorger’s Gauntlets, Tassets of the Dawning Sky |
Echo of the Varshan Loot Table
Locate the Malignant Burrow dungeon near the Tree of Whispers in Hawezar. You need to complete the quest of the Whispers of the Dead and collect the body parts of Varshan to summon it. Ensure being well-prepared for this dungeon and have the ideal builds to clear this dungeon.

You will get one of the following Uniques once you defeat Echo of the Varshan:
Character Classes | Uniques |
Necromancer | Ring of the Sacrilegious Soul, Deathless Visage, Bloodless Scream, Deathspeaker’s Pendant |
Rogue | Eyes in the Dark, Writhing Band of Trickery, Condemnation, Skyhunter |
Sorcerer | Raiment of the Infinite, Esu’s Heirloom, Staff of Endless Rage, Tal Rasha’s Iridescent Loop |
Barbarian | Gohr’s Devastating Grips, Fields of Crimson, Ring of Red Furor |
Druid | Greatstaff of the Crone, Airidah’s Inexorable Will, Mad Wolf’s Glee, Vasily’s Prayer |
All classes | Mother’s Embrace, Frostburn |
Grigoire the Galvanic Saint loot table
Navigate your way to the Dindai Flats zone of Dry Steppes. Make sure that you have acquired Living Steel from participating in the Helltide Events. Enter the Penitent dungeon and summon the boss Grigoire using the resources.

After you defeat Grigoire, you will get one of the following Uniques:
Character Classes | Uniques |
Necromancer | Ebonpiercer, Blood Artisan’s Cuirass, Greaves of the Empty Tomb, Howl from Below |
Rogue | Saboteur’s Signet, Word of Hakan, Windforce, Grasp of Shadow |
Sorcerer | Gloves of the Illuminator, Staff of Lam Esen, Flameweaver, Iceheart Brais |
Barbarian | The Butcher’s Cleaver, Ramaladni’s Magnum Opus, Ancients’ Oath, Twin Strikes, Rage of Harrogath, Battle Trance |
Druid | Waxing Gibbous, Insatiable Fury, The Butcher’s Cleaver, Earthbreaker, Hunter’s Zenith |
All classes | Penitent Greaves |
Uber Duriel loot table
Defeat the two bosses Echo of the Varshan and Grigoire to acquire the Mucus-Slick Egg and the Shard of Agony. Once you have these items, go to the Southern Expanse zone in Khejistan and locate the Gaping Crevasse dungeon. Enter the dungeon and use the items to summon the Uber Duriel boss.

Defeat Uber Duriel to get the following Uniques:
Character Classes | Uniques |
Necromancer | Black River, Blood Moon Breaches |
Rogue | Cowl of the Nameless, Scoundrel’s Leathers |
Sorcerer | Blue Rose, Flamescar |
Barbarian | Tuskhelm of Joritz the Mighty, Azurewrath |
Druid | Dolmen Stone, Tempest Roar |
All classes | Tibault’s Will, Soulbrand, Godslayer Crown Flickerstep, Banished Lord’s Talisman, X’Fal’s Corroded Signet |
Uber Andariel loot table
Obtain the Sandscorched Shackles and the Pincushioned Doll by defeating Lord Zir and Beast in the Ice. Make your way to Scouring Sands in Kehjistan and enter the Hanged Man’s Hall. Use the items you previously acquired to activate the Altar of Anguish and summon the boss Uber Andariel.

You will get one of the following Uniques once you defeat Uber Andariel:
Character Classes | Uniques |
Necromancer | Doombringer, The Grandfather |
Rogue | Doombringer |
Sorcerer | Spear of Lycander, Ahavarion |
Barbarian | The Grandfather, Doombringer |
Druid | Ahavarion, Spear of Lycander |
All classes | Ring of Starless Skies, Harlequin Crest, Melted Heart of Selig, Tyrael’s Might, Andariel’s Visage |